Antibacterial Activity of Leucaena leucocephala Extracts on Growth of Escherichia coli

Rosida, Dedin F and Djajati, Sri and Nilamayu, Z.A and Rosida, Rosida (2017) Antibacterial Activity of Leucaena leucocephala Extracts on Growth of Escherichia coli. Advanced Science Letters, 23. pp. 12268-12271.

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Abstract

Enhancement of pathogenic bacteria such as gram-negative bacteria (Escherichia coli) and gram-positive bacteria (Staphylococcus aureus) can cause diseases such as diarrhea, nausea, abdominal pain and fever. Utilization of medicinal plants as an herbal remedy for preventing and treating the disease continues to evolve in development of the medical field to obtain material resources as new antibiotics. The use of Leucaena leucocephala extracts with various solvent to determine the antibacterial activity was a novelty research of leucaena. Analysis of antibacterial activity was done by two methods, inhibition zone and Total Plate Count. In this study used two factors. The first factor was the type of leucaena seeds (mature and immature seeds) and the second factor was type of solvent (water, ethanol and hexane). The results of leucaena extract identificated compound of saponin, tannin, alkaloid and terpenoid, total phenol of 523.87 mg/L. The highest antibacterial activity of Escherichia coli was founded in mature seed extract with water solvent at a concentration of 100% had inhibition zone of 19 mm (positive control of 29 mm) and Total Plate Count of bacterial growth of 2�11 × 107 (CFU/ml) in line a negative control 7�78 × 105 (CFU/ml) and positive control 0�94 × 107 (CFU/ml). IP: 182.255.1.11 On: Thu, 17 May 2018 07:10:50 Copyright: American Scientific Publishers Delivered by Ingenta Keywords: L. leucocephala, Active Compounds, Antibacterial, Escherichia coli, Inhibition Zone.

Item Type: Article
Subjects: T Technology > TP Chemical technology > TP368 Food processing and manufacture
Divisions: Faculty of Engineering > Departement of Food Engineering
Depositing User: Fatchullah Fatchullah
Date Deposited: 26 Dec 2022 10:41
Last Modified: 26 Dec 2022 10:41
URI: http://repository.upnjatim.ac.id/id/eprint/10614

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