Laulista, Belinda (2025) SINTESIS BIOKOMPOSIT NANOFIBER DARI PLA (Polylactic Acid), SELULOSA, DAN KITOSAN DENGAN PROSES ELECTROSPINNING UNTUK APLIKASI WOUND DRESSING (PEMBALUT LUKA). Undergraduate thesis, UPN VETERAN JAWA TIMUR.
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Abstract
Wound healing is a complex process involving hemostasis, inflammation, proliferation, and maturation phases, where ideal wound dressings play a critical role in preventing infection and accelerating tissue regeneration. However, conventional synthetic plastic dressings pose severe environmental concerns due to their non-biodegradable nature. To address this issue, eco-friendly polymer-based nanofiber dressings synthesized via electrospinning have gained significant attention because their structure mimics the natural extracellular matrix of the skin. Poly(lactic acid) (PLA) is highly favored for biomedical applications due to its biocompatibility and biodegradability, yet its inherent brittleness limits its mechanical performance. To overcome this limitation, incorporating cellulose as a reinforcing agent can significantly enhance tensile strength and water retention, while adding chitosan introduces vital antibacterial and anti-inflammatory properties to prevent wound infections. Previous studies indicate that optimal formulations, such as a 3% chitosan blend or a 3% modified nanocrystalline cellulose (QACNC) integration, yield superior mechanical strength and bacterial inhibition. Building upon these findings, this study focuses on the synthesis of a PLA/cellulose/chitosan biocomposite nanofiber via electrospinning to evaluate its performance, ultimately aiming to serve as a comprehensive reference for developing highly effective, environmentally friendly advanced wound dressings.
| Item Type: | Thesis (Undergraduate) | ||||||||
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| Subjects: | Q Science > QD Chemistry | ||||||||
| Divisions: | Faculty of Engineering > Departement of Chemical Engineering | ||||||||
| Depositing User: | belinda belinda laulista belinda | ||||||||
| Date Deposited: | 29 May 2026 02:27 | ||||||||
| Last Modified: | 29 May 2026 02:27 | ||||||||
| URI: | https://repository.upnjatim.ac.id/id/eprint/52604 |
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